Nom du corpus

Corpus Systématique Animale

Titre du document

Comparative studies of ?-Lactalbumin and lysozyme: Echidna lysozyme

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Nom du fichier dans la ressource
Mammiferes_v2b_00245
Auteur(s)
  • K. E. Hopper 1
  • H. A. McKenzie 1
Affiliation(s)
  • 1) Depart. of Physical Biochemistry, Institute of Advanced Studies, Australian National University, Canberra, ACT
Résumé

?-Lactalbumin is a modifier protein for galactosyl transferase in the biosynthesis of lactose and lysozyme catalyses the cleavage of ?(1–4) glycosidic linkages. It is now generally believed that ?-lactalbumin and lysozyme have diverged from a common ancestor. Comparative studies of these proteins from several species are reported here. The presence of lactose and lactose synthetase activity is shown in mature milk samples from a variety of placental mammals (eutheria) and a pouch bearing mammal (marsupialia). The isolation of the ?-lactalbumins involved and their properties are compared. The position is different in the milk samples of monotremes. The ?-lactalbumin, lactose and lactose synthetase activity levels in the two platypus samples studied are very low. The levels of lactose and lactose synthetase activity in some echidna(Tachyglossus aculeatus) samples are low, but appreciable in others. No ?-lactalbumin is present. The lysozyme activity is appreciable, some samples containing a different lysozyme from that present in others. One of these (designated echidna lysozyme I) is capable of lactose synthetase modifier activity in the presence of bovine “A protein”. The properties of this lysozyme are compared with those of lysozymes and ?-lactalbumins from a variety of species and their significance is discussed.

Catégories Science-Metrix
  • 1 - health sciences
  • 2 - biomedical research
  • 3 - biochemistry & molecular biology
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
  • 4 - genetique des eucaryotes. evolution biologique et moleculaire
Catégories Scopus
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Cell Biology
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Clinical Biochemistry
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Molecular Biology
  • 1 - Health Sciences ; 2 - Medicine ; 3 - General Medicine
Catégories WoS
  • 1 - science ; 2 - cell biology
Identifiant ISTEX
00B30E08E8F07AF4388DEC16CD6FF2CC9E15C2B2
Revue

Molecular and Cellular Biochemistry

Année de publication
1974
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
9.364
Sous-corpus
  • Mammiferes
Type de publication
Journal
ark:/67375/1BB-D3H9P8XB-S
Powered by Lodex 9.3.8