Nom du corpus

Corpus Systématique Animale

Titre du document

A comparative study of gangliosides from the brains of various species

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Nom du fichier dans la ressource
Batraciens_v2b_00198, Mammiferes_v2b_01061, Oiseaux_v2b_01106, Poissons_v2b_001907, Reptiles_v2b_00310
Auteur(s)
  • C. -L. Schengrund 1
  • O. W. Garrigan 1
Affiliation(s)
  • 1) Department of Chemistry, Seton Hall University, 07079, South Orange, New Jersey
Résumé

A comparison is made of the sialic acid and hexose content of crude gangliosides from the brains of 13 species, including mammals, a bird, and amphibian, a reptile and fish. The sialic acid content is relatively constant from species to species. Gangliosides are less abundant in tissues other than the brain. Four species (cat, dog, pig and sheep) were selected for the determination of their major ganglioside subfractions. The ganglioside subfractions were isolated (after extraction and partition dialysis) using descending thin layer chromatography. The population of ganglioside molecules varied from species to species. From dog and sheep a mono-, a di- and a trisialoganglioside were obtained; from cat a mono-, a di- and two trisialogangliosides; and from pig a mono- and two disialogangliosides. Each ganglioside subfraction was found to contain glucose, galactose and galactosamine in the ratio of approximately 1?2?1. The fatty acid moieties consisted of more than 80% stearic acid with lesser amounts of arachidic, palmitic and behenic acid. Sphingosine analyses indicated ratios of sphingosine to icosisphingosine of 7?3 for the monosialo-, 1?1 for the disialo- and 3?7 for the trisialogangliosides.

Catégories Science-Metrix
  • 1 - health sciences
  • 2 - biomedical research
  • 3 - nutrition & dietetics
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
  • 4 - biochimie analytique, structurale et metabolique
Catégories Scopus
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Cell Biology
  • 1 - Physical Sciences ; 2 - Chemistry ; 3 - Organic Chemistry
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Biochemistry
Catégories WoS
  • 1 - science ; 2 - nutrition & dietetics
  • 1 - science ; 2 - biochemistry & molecular biology
Identifiant ISTEX
F407916C98AFEBB538D5D90A5F4277F8E51DE5FE
Revue

Lipids

Année de publication
1969
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
9.196
Sous-corpus
  • Batraciens
  • Mammiferes
  • Oiseaux
  • Poissons
  • Reptiles
Type de publication
Journal
ark:/67375/1BB-BTBW82MN-9
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