Nom du corpus

Corpus Systématique Animale

Titre du document

Lens protein expression in mammals: Taxon-specificity and the recruitment of crystallins

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Mots-clés d'auteur
  • Lens
  • Crystallins
  • Macroscelids
  • Marsupials
  • Protein evolution
  • Enzymes
Nom du fichier dans la ressource
Mammiferes_v2b_00182
Auteur(s)
  • Graeme Wistow 1
  • Hyong Kim 1
Affiliation(s)
  • 1) Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Room 204, Building 6, 20892, Bethesda, Maryland, USA
Résumé

Vertebrate lenses show remarkably taxon-specific patterns of protein composition, most obviously in the recruitment of enzymes as major crystallins. Phylogenetic relationships are particularly apparent in mammals. Here we describe ?-crystallin, which is probably identical to cytosolic aldehyde dehydrogenase, lens-specifically expressed at high abundance in the elephant shrews, primitive eutherians of the family Macroscelidae, and ?-crystallin, a novel lens protein expressed in some marsupials. We have also observed that enzymes that have been recruited as crystallins in some species are also moderately abundant in the lenses of other species. This hints that the origins of enzyme-crystallins may lie in a pool of enzymes widely expressed in lenses at fairly high levels, perhaps because they have important developmental or functional roles in the tissue.

Catégories Science-Metrix
  • 1 - natural sciences
  • 2 - biology
  • 3 - evolutionary biology
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
Catégories Scopus
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Genetics
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Molecular Biology
  • 1 - Life Sciences ; 2 - Agricultural and Biological Sciences ; 3 - Ecology, Evolution, Behavior and Systematics
Catégories WoS
  • 1 - science ; 2 - genetics & heredity
  • 1 - science ; 2 - evolutionary biology
  • 1 - science ; 2 - biochemistry & molecular biology
Identifiant ISTEX
3F2BA15452A7AE2A2170213DDBC2D9405E3CE7F2
Revue

Journal of Molecular Evolution

Année de publication
1991
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
8.476
Sous-corpus
  • Mammiferes
Type de publication
Journal
ark:/67375/1BB-9WG72726-W
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