Nom du corpus

Corpus Systématique Animale

Titre du document

Environmental contaminants and biochemical responses in flatfish from the Hvaler Archipelago in Norway

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Nom du fichier dans la ressource
Poissons_v2b_001551
Auteur(s)
  • Anders Goksøyr 1
  • Astrid -Mette Husøy 1
  • Håvard E. Larsen 1
  • Jarle Klungsøyr 2
  • Svein Wilhelmsen 2
  • Amund Maage 3
  • Einar M. Brevik 4
  • Tommy Andersson 5
  • Malin Celander 5
  • Maija Pesonen 5
  • Lars Förlin 5
Affiliation(s)
  • 1) Department of Biochemistry, University of Bergen, Årstadveien 19, N-5009, Bergen, Norway
  • 2) Institute of Marine Research, N-5024, Bergen, Norway
  • 3) Directorate of Fisheries, Institute of Nutrition, N-5024, Bergen, Norway
  • 4) Norwegian Institute for Air Research, N-2000, Lillestrøm, Norway
  • 5) Department of Zoophysiology, University of Göteborg, S-400 31, Göteborg, Sweden
Résumé

The levels of several environmental contaminants, including selected polyaromatic hydrocarbons (PAH), organochlorines (DDT/DDE, hexachlorobenzene), 15 polychlorinated biphenyl (PCB) congeners, and polychlorinated dibenzofurans and dibenzo-p-dioxins, PCDF/PCDD), and heavy metals (Cd, Hg, Pb, and As) were analyzed in muscle and liver of three different flatfish species (dab,Limanda limanda; flounder,Platichthys flesus; plaice,Pleuronectes platessa) caught by gill netting at different sites in the Hvaler Archipelago. Indices of biochemical effects in liver S9-fractions were studied by measuring cytochrome P450-dependent monooxygenase and UDP-glucuronyl transferase activities, and by immunoquantitating cytochrome P450 1A1 using an indirect enzyme-linked immunosorbent assay (ELISA). Only low levels of PCDD/PCDF, Cd, and Pb were observed, whereas PCB levels were significantly elevated in fish from the inner sites of the Archipelago compared to a reference site. The contaminant gradient toward the Glomma estuary was correlated with increased cytochrome P450 1A1 activity, measured as 7-ethoxyresorufin O-deethylase (EROD), and with immunoquantitated P450 1A1. In contrast, fish from the site at Idefjorden, although containing elevated contaminant levels, did not show elevated EROD activity, but apparently elevated P450 1A1 protein. These findings may reflect different pollution histories of the sites, and indicate the applicability of biochemical effect indices (i.e., EROD and P450 1A1 immunoquantitation) to monitoring studies. The integrated chemical-biochemical approach employed in this study can obviously be expanded to give fruitful information about cause-effect relationships in other contaminant situations.

Catégories Science-Metrix
  • 1 - health sciences
  • 2 - biomedical research
  • 3 - toxicology
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
  • 4 - psychologie. psychophysiologie
Catégories Scopus
  • 1 - Physical Sciences ; 2 - Environmental Science ; 3 - Health, Toxicology and Mutagenesis
  • 1 - Physical Sciences ; 2 - Environmental Science ; 3 - Pollution
  • 1 - Life Sciences ; 2 - Pharmacology, Toxicology and Pharmaceutics ; 3 - Toxicology
  • 1 - Health Sciences ; 2 - Medicine ; 3 - General Medicine
Catégories WoS
  • 1 - science ; 2 - toxicology
  • 1 - science ; 2 - environmental sciences
Identifiant ISTEX
8CA0D511CE7752844FE3081328AB9116354EB5DE
Revue

Archives of Environmental Contamination and Toxicology

Année de publication
1991
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
9.676
Sous-corpus
  • Poissons
Type de publication
Journal
ark:/67375/1BB-9TST96X7-6
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