Nom du corpus

Corpus Systématique Animale

Titre du document

An investigation of the homology of guanylate kinase isozymes in mammals and further evidence for multiple GUK gene loci

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Mots-clés d'auteur
  • guanylate guanylate kinase
  • homologous genes
  • allelic variation
Nom du fichier dans la ressource
Mammiferes_v2b_01064
Auteur(s)
  • Talat Jamil 1
  • Rachel A. Fisher 1
Affiliation(s)
  • 1) MRC Human Biochemical Genetics Unit, The Galton Laboratory, University College London, England
Résumé

Guanylate kinase in the red cells of 63 different mammalian species was studied by electrophoresis and multiple molecular forms of the enzyme were found in all species. Two species were investigated in more detail. Using molecular weight estimates as a criterion of homology, the fallow deer and the Chinese hamster were found to have isozymes that corresponded to isozymes e, f, and g of man. Variation in the guanylate kinase isozymes was detected in a small population of orangutans. Results suggested that isozymes a and b were monomeric and that they were the products of a gene locus, GUK 1 , different from the locus GUK 3 which coded for isozymes e, f, and g. Products c and d of the presumptive GUK 2 locus were not found in the orangutan.

Catégories Science-Metrix
  • 1 - natural sciences
  • 2 - biology
  • 3 - evolutionary biology
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
  • 4 - psychologie. psychophysiologie
Catégories Scopus
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Genetics
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Molecular Biology
  • 1 - Health Sciences ; 2 - Medicine ; 3 - General Medicine
  • 1 - Life Sciences ; 2 - Agricultural and Biological Sciences ; 3 - Ecology, Evolution, Behavior and Systematics
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Biochemistry
Catégories WoS
  • 1 - science ; 2 - genetics & heredity
  • 1 - science ; 2 - biochemistry & molecular biology
Identifiant ISTEX
0DC616F9AADF8A591CEDA7281E088FC395B48DD4
Revue

Biochemical Genetics

Année de publication
1977
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
7.04
Sous-corpus
  • Mammiferes
Type de publication
Journal
ark:/67375/1BB-5J0LCRDD-V
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