Nom du corpus

Corpus Systématique Animale

Titre du document

Different bioavailability in humans of wheat and fish selenium as measured by blood platelet response to increased dietary Se

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Mots-clés d'auteur
  • Selenium
  • fish selenium
  • wheat selenium
  • bioavailability
  • mercury
  • arsenium
  • humans
Nom du fichier dans la ressource
Poissons_v2b_004565
Auteur(s)
  • Helle M. Meltzer 1
  • Karen Bibow 2
  • Irene T. Paulsen 1
  • Håvard H. Mundal 3
  • Gunnar Norheim 4
  • Halvor Holm 1
Affiliation(s)
  • 1) Institute for Nutrition Research University of Oslo, PO Box 1046, N-0316, Oslo, Norway
  • 2) Department of Chemistry, University of Oslo, PO Box 1033, N-0315, Oslo, Norway
  • 3) Department of Internal Medicine, Ullevål Hospital, N-0407, Oslo, Norway
  • 4) Department of Pharmacology and Toxicology, Norwegian College of Veterinary Medicine/National Veterinary Institute, N-0033, Oslo, Norway
Résumé

The bioavailabilities of selenium (Se) from Se-rich fish species and Se-rich wheat were compared in a study involving 32 healthy volunteers. Initial serum Se values were 109±16 ?g/L (mean±SD). For 6 wk, one group (n=11) included Se-rich bread in their diet, bringing daily average intake of Se up to 135±25 ?g/d. Another group (n=11) consumed Se-rich fish daily (average Se intake: 115±31 ?g/d), whereas the control group (n=10) ate their normal diet, providing 77±25 ?g Se/d. Serum Se increased by 17% (P<0.01), and platelet Se increased by 30% (P<0.01) in the wheat group. Although platelet Se decreased by 11% in the fish group, no changes in serum and platelet Se in the fish or control group reached statistical significance. Glutathione peroxidase (EC 1.11.1.9; GSH-Px) activity in serum and platelets did not change during the study, nor did platelet mercury (Hg) content. Since the dietary intake of Hg, arsenium (As), and fatty acids could not satisfactorily explain the lack of response in the fish group, the results are indicative of low bioavailability of fish Se in humans. At present, wheat Se seems to be the most important factor contributing to the body stores of Se in this study population.

Catégories Science-Metrix
  • 1 - health sciences
  • 2 - biomedical research
  • 3 - toxicology
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences medicales
Catégories Scopus
  • 1 - Health Sciences ; 2 - Medicine ; 3 - Biochemistry, medical
  • 1 - Physical Sciences ; 2 - Chemistry ; 3 - Inorganic Chemistry
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Clinical Biochemistry
  • 1 - Health Sciences ; 2 - Medicine ; 3 - General Medicine
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Biochemistry
  • 1 - Health Sciences ; 2 - Medicine ; 3 - Endocrinology, Diabetes and Metabolism
Catégories WoS
  • 1 - science ; 2 - endocrinology & metabolism
  • 1 - science ; 2 - biochemistry & molecular biology
Identifiant ISTEX
633C7AF98571BF02A0D6033CD915ADA0FA7FC811
Revue

Biological Trace Element Research

Année de publication
1993
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
8.911
Sous-corpus
  • Poissons
Type de publication
Journal
ark:/67375/1BB-51QH0TWT-B
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