Nom du corpus

Corpus Systématique Animale

Titre du document

Phylogenetic conservation and physical mapping of members of the H6 homeobox gene family

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Nom du fichier dans la ressource
Echinodermes_v2b_0337
Auteur(s)
  • H. S. Stadler 1
  • J. C. Murray 2
  • N. J. Leysens 2
  • P. J. Goodfellow 3
  • M. Solursh 1
Affiliation(s)
  • 1) Department of Biological Sciences, University of Iowa, 52242, Iowa City, Iowa, USA
  • 2) Cooperative Human Linkage Center, 431 EMRB, University of Iowa, 52242, Iowa City, Iowa, USA
  • 3) Department of Surgery, Washington University School of Medicine, 63110, St. Louis, Missouri, USA
Résumé

Homeobox genes represent a class of transcription factors that play key roles in the regulation of embryogenesis and development. Here we report the identification of a homeobox-containing gene family that is highly conserved at both the nucleotide and amino acid levels in a diverse number of species. These species encompass both vertebrate and invertebrate phylogenies, ranging from Homo sapiens to Drosophila melanogaster. In humans, at least two homeobox sequences from this family were identified representing a previously reported member of this family as well as a novel homeobox sequence that we physically mapped to the 10q25.2–q26.3 region of human Chromosome (Chr) 10. Multiple members of this family were also detected in three additional vertebrate species including Equus caballus (horse), Gallus gallus (Chicken), and Mus musculus (mouse), whereas only single members were detected in Tripneustes gratilla (sea urchin), Petromyzon marinus (lamprey), Salmo salar (salmon), Ovis aries (sheep), and D. melanogaster (fruit fly).

Catégories Science-Metrix
  • 1 - health sciences
  • 2 - biomedical research
  • 3 - genetics & heredity
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
  • 4 - ecologie animale, vegetale et microbienne
Catégories Scopus
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Genetics
Catégories WoS
  • 1 - science ; 2 - genetics & heredity
  • 1 - science ; 2 - biotechnology & applied microbiology
  • 1 - science ; 2 - biochemistry & molecular biology
Identifiant ISTEX
FD3FA7A5284007B2E8E89352B2AECE978FE0A0E4
Revue

Mammalian Genome

Année de publication
1995
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
8.14
Sous-corpus
  • Echinodermes
Type de publication
Journal
ark:/67375/1BB-422FH8F9-8
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