Nom du corpus

Corpus Systématique Animale

Titre du document

A defective non-LTR retrotransposon is dispersed throughout the genome of the silkworm, Bombyx mori

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Nom du fichier dans la ressource
Mammiferes_v2b_01119
Auteur(s)
  • Teru Ogura 1
  • Kazuhiro Okano 2
  • Kozo Tsuchida 2
  • Naoko Miyajima 2
  • Hideho Tanaka 3
  • Naoko Takada 2
  • Susumu Izumi 4
  • Shiro Tomino 4
  • Hideaki Maekawa 2
Affiliation(s)
  • 1) Department of Molecular Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University School of Medicine, 862, Kumamoto, Japan
  • 2) Division of Radiation Control and Biology, National Institute of Health, 162, Tokyo, Japan
  • 3) Biosciences Laboratory, Research Center, Mitsubishi Chemical Industries Limited, 227, Yokohama, Japan
  • 4) Department of Biology, Faculty of Science, Tokyo Metropolitan University, 158, Tokyo, Japan
Résumé

The presence of long repetitive sequences is demonstrated in the genome of the silkworm, Bombyx mori. Members of this BMC1 family reveal several features typical of the L1 (long interspersed sequence one) family of mammals, except for species specific elements. The number of BMC1 elements is estimated to be approximately 3500 per haploid genome. Elements containing the full length unit of 5.1 kb are dispersed throughout the genome and their restriction sites are conserved, although most members are preferentially truncated to varying extents at their 5? ends. DNA sequencing indicates that this element contains six tandem repeats of 15 bp CpG-rich sequence in the 5? proximal region. It terminates with a 3? oligo(A) stretch, and is flanked at both ends by a 7–10 bp target sequence duplication. In addition, there is significant evidence for amino acid sequence homology with reverse transcriptase domains of other L1 families, especially F, Doc and lockey of Drosophila melanogaster. No large open reading frame is present. The BMC1 element is suggested to be dispersed in the genome by a transposition mechanism involving RNA intermediates.

Catégories Science-Metrix
  • 1 - health sciences
  • 2 - biomedical research
  • 3 - developmental biology
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
  • 4 - psychologie. psychophysiologie
Catégories Scopus
  • 1 - Health Sciences ; 2 - Medicine ; 3 - Genetics(clinical)
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Genetics
Catégories WoS
  • 1 - science ; 2 - genetics & heredity
  • 1 - science ; 2 - biochemistry & molecular biology
Identifiant ISTEX
07FAFFFDC53C2509F387DFFA65A374F23685E251
Revue

Chromosoma

Année de publication
1994
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
9.16
Sous-corpus
  • Mammiferes
Type de publication
Journal
ark:/67375/1BB-40TJVF5L-4
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