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Corpus Systématique Animale

Titre du document

Evolution of the larval cuticle proteins coded by the secondary sex chromosome pair: X2 and neo-Y of Drosophila miranda: II. Comparison at the amino acid sequence level

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Springer (journals)
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Type de document
Mots-clés d'auteur
  • Drosophila
  • Cuticle proteins (LCP)
  • Conserved protein motifs
  • Gene phylogeny
  • Sex chromosomes
Nom du fichier dans la ressource
  • Manfred Steinemann 1
  • Sigrid Steinemann 1
  • Wilhelm Pinsker 2
  • 1) Institut für Genetik, Heinrich Heine Universität Düsseldorf, Universitätsstr. 1, D-40225, Düsseldorf, FR Germany
  • 2) Institut für Medizinische Biologie, Abt. Genetik, Universität Wien, Währingerstr. 17, A-1090, Wien, Austria

The larval cuticle proteins (LCPs) are encoded by a multigene family,Lcp1-4, located at the right arm of the metacentric autosome 2 (2R) inDrosophila melanogaster. Due to a chromosome fusion theLcp locus ofDrosophila miranda is situated on a pair of secondary sex chromosomes, theX2 andneo-Y chromosomes. Comparing the deduced amino acid sequences of the autosomalD. melanogaster loci with the sex-chromosomal loci ofD. miranda, we were able to trace the evolution of theLcp loci with respect to their different chromosomal inheritance. The length of the signal peptide is conserved in all four LCPs, while the size of the mature LCPs varies. Conserved protein motifs became obvious from the alignment, indicating regions of structural and functional importance. Analyzing intra- and interspecific sequence similarities of theLcp gene families allowed us to reconstruct the phylogeny of the gene cluster. Alignment with cuticle amino acid sequences originating from divergent insect species reveals motifs already present in the primordial insect LCPs. These motifs indicate different levels of constraint acting during the evolution of the LCPs.

Catégories Science-Metrix
  • 1 - natural sciences
  • 2 - biology
  • 3 - evolutionary biology
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
  • 4 - vertebres: reproduction
Catégories Scopus
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Genetics
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Molecular Biology
  • 1 - Life Sciences ; 2 - Agricultural and Biological Sciences ; 3 - Ecology, Evolution, Behavior and Systematics
Catégories WoS
  • 1 - science ; 2 - genetics & heredity
  • 1 - science ; 2 - evolutionary biology
  • 1 - science ; 2 - biochemistry & molecular biology
Identifiant ISTEX

Journal of Molecular Evolution

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Score qualité du texte
  • Insectes
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