Nom du corpus

Corpus Systématique Animale

Titre du document

A monoclonal mouse antiallotype antibody reacts with certain human and other vertebrate immunoglobulins: Genetic and phylogenetic findings

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Nom du fichier dans la ressource
Batraciens_v2b_00277, Mammiferes_v2b_01406, Oiseaux_v2b_01512, Poissons_v2b_002690, Reptiles_v2b_00445
Auteur(s)
  • Marilyn Parsons 1
  • Leonard A. Herzenberg 1
Affiliation(s)
  • 1) Department of Genetics, Stanford University School of Medicine, 94305, Stanford, California
Résumé

A new mouse monoclonal antibody, 18.1, recognizes an allotypic determinant on mouse IgG1 of the “a” allotype. We found that this alloantibody reacts with immunoglobulins of evolutionary distant vertebrate species including man, and with only certain isotypes or allotypes in some of these species. Most mammalian sera are reactive, except those from lagomorphs, marsupials, and monotremes. Avian and reptilian sera are also positive, while the amphibian and fish sera tested were negative. In human sera, 18.1 detects an isotypic marker on IgG2 and an allotypic marker on IgG3. This reactivity parallels the distribution of the Gm non-g determinant. These findings are discussed in relation to the phylogeny of IgG and its subclasses.

Catégories Science-Metrix
  • 1 - health sciences
  • 2 - clinical medicine
  • 3 - immunology
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
  • 4 - immunologie fondamentale
Catégories Scopus
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Genetics
  • 1 - Life Sciences ; 2 - Immunology and Microbiology ; 3 - Immunology
Catégories WoS
  • 1 - science ; 2 - immunology
  • 1 - science ; 2 - genetics & heredity
Identifiant ISTEX
2D13D42E151E3C53052561F72B1CD487675CA427
Revue

Immunogenetics

Année de publication
1981
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
8.356
Sous-corpus
  • Batraciens
  • Mammiferes
  • Oiseaux
  • Poissons
  • Reptiles
Type de publication
Journal
ark:/67375/1BB-3HXJ9H0C-8
Powered by Lodex 9.3.8