Nom du corpus

Corpus Systématique Animale

Titre du document

Idiogram and trisomy of the water vole ( Arvicola terrestris L.), a favourable animal for cytogenetic research

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Nom du fichier dans la ressource
Mammiferes_v2b_02651
Auteur(s)
  • Karl Fredga
Affiliation(s)
  • Institute of Genetics, Lund, Sweden
Résumé

The chromosomes of the water vole (Arvicola terrestris L.) were investigated in 2 female and 5 male animals from three different parts of Sweden. The somatic chromosomes were studied in direct preparations of cornea and bone marrow and in tissue cultures of testis, lung and heart. Meiosis was studied in one male. The chromosome number was 2n=36. No differences in regard to chromosome number and morphology were found among the seven control animals studied. Different chromosome types are represented and the karyotype of the species is favourable for chromosome studies. — An idiogram of the water vole was constructed from measurements of complete chromosome sets from ten heart cells. — In addition to the above normal material one young water vole, trapped in nature, was found to have 37 chromosomes and was trisomic for the smallest autosome. This autosome had a secondary constriction and took part in “satellite associations”. The cytologic similarities to Down's syndrome in man are striking and it is hoped that the water vole will become a valuable laboratory mammal, especially for elucidation of the chromosomal mechanisms of non-disjunction. The trisomic water vole had no obvious phenotypic abnormalities, but at least one feature was not within normal limits — its tail was unusually short. Also, the development of certain teeth was somewhat aberrant. Whether short tail and dental deformities are symptoms correlated with trisomy for the smallest autosome in the water vole is an open question so far.

Catégories Science-Metrix
  • 1 - health sciences
  • 2 - biomedical research
  • 3 - developmental biology
Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
Catégories Scopus
  • 1 - Health Sciences ; 2 - Medicine ; 3 - Genetics(clinical)
  • 1 - Life Sciences ; 2 - Biochemistry, Genetics and Molecular Biology ; 3 - Genetics
Catégories WoS
  • 1 - science ; 2 - genetics & heredity
  • 1 - science ; 2 - biochemistry & molecular biology
Identifiant ISTEX
568C22503BB8BA622987C8F9B6AE56B5407182AF
Revue

Chromosoma

Année de publication
1968
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
9.904
Sous-corpus
  • Mammiferes
Type de publication
Journal
ark:/67375/1BB-2PZDVRH4-L
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