Nom du corpus

Corpus Systématique Animale

Titre du document

In vitro properties of heterologous anti-lizard thymocyte serum

Lien vers le document
Éditeur
Springer (journals)
Langue(s) du document
Anglais
Type de document
Research-article
Nom du fichier dans la ressource
Reptiles_v2b_00844
Auteur(s)
  • RM. Pitchappan 1
  • VR. Muthukkaruppan 1
Affiliation(s)
  • 1) Department of Biological Sciences, Madurai University, 625021, Madurai
Résumé

A potent and specific antiserum was raised in rabbits by injecting a single cell suspension of thymocytes of the lizard,Calotes versicolor. Rabbit anti-Calotes thymocyte serum (ATS) was characterizedin vitro by using cytotoxicity assay and quantitative absorption analysis. The cytolytic activity of ATS was always higher towards thymocytes than towards lymphoid cells of spleen, bone-marrow and peripheral blood. Various absorption experiments indicate the existence of two antigens among thymocytes—one distinct for thymocytes and thymus derived cells and another, common to lymphocytes. Further, thymus-brain antigenic correlation has been demonstrated in this reptilian species. TheCalotes complement is less efficient than that of guinea pig in mediating the cytolysis of target cells by ATS. Further, ATS did not have cytotoxic effect on antibody producing cells. The significance of these findings has been discussed with reference to the dichotomy of lymphoid systems at this phylogenetic level.

Catégories INIST
  • 1 - sciences appliquees, technologies et medecines
  • 2 - sciences biologiques et medicales
  • 3 - sciences biologiques fondamentales et appliquees. psychologie
  • 4 - ethologie animale
Identifiant ISTEX
50EFD58AA6FCD783541CA67ADC3F48EBFF72A34E
Revue

Proceedings of the Indian Academy of Sciences - Section B

Année de publication
1977
Présence de XML structuré
Non
Version PDF
1.3
Score qualité du texte
7.077
Sous-corpus
  • Reptiles
Type de publication
Journal
ark:/67375/1BB-18WHN18D-B
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